Theory of Tunable pH-Sensitive Vesicles of Anionic and Cationic Lipids or Anionic and Neutral Lipids
نویسندگان
چکیده
منابع مشابه
Theory of tunable pH-sensitive vesicles of anionic and cationic lipids or anionic and neutral lipids.
The design of vesicles that become unstable at an easily tuned value of pH is of great interest for targeted drug delivery. We present a microscopic theory for two forms of such vesicles. A model of lipids introduced by us previously is applied to a system of ionizable anionic lipid and permanently charged cationic lipid. We calculate the pH at which the lamellar phase becomes unstable with res...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2001
ISSN: 0006-3495
DOI: 10.1016/s0006-3495(01)76141-3